transaminitis and pulmonary findings can confound a diagnosis of preeclampsia or HELLP syndrome).

Laboratory abnormalities may overlap with obstetric diagnoses (e.g.

If a patient is presenting with COVID-like symptoms, particularly a fever, a high clinical suspicion for alternative or comorbid processes such as chorioamnionitis, pyelonephritis, malaria, or influenza is needed.

The clinical presentation for COVID-19 can mirror other diseases in pregnancy and other diseases can mimic COVID-19. A series of 215 pregnant patients from New York demonstrated a 13.7% rate of positive nasopharyngeal swab testing for SARS-CoV2 amongst asymptomatic women ( Sutton et al ). Depending on local epidemiology, prevalence in asymptomatic pregnant women may be high enough to warrant universal screening. In one systematic review, 75% of positive mothers in universal screening were asymptomatic, and only 25% were symptomatic ( Allotey et al). Rates of asymptomatic and pre-symptomatic infection amongst pregnant women vary in different studies. Asymptomatic and Presymptomatic Infection Copy Link!

In a study of 23,000 pregnant and 386,000 non-pregnant women with symptomatic COVID-19, the most frequently reported symptoms among pregnant women were cough (50%), headache (43%), muscle aches (37%), fever (32%), sore throat (28%), shortness of breath (26%), chills (24%), loss of taste or smell (22%), nausea or vomiting (20%), diarrhea (14%), runny nose (13%), fatigue (13%) and abdominal pain (8%). In general, pregnant women present with signs and symptoms similar to the non-pregnant population ( Zaigham Wu et al Liu et al Afshar). Updated Date: FebruSigns and Symptoms Copy Link! Clinical Course in Pregnancy Copy Link! Clinical Presentation Copy Link!

Tool: PIH Flow Chart of Pregnancy Care During the COVID-19 Pandemic, From Screening and Triage Through Labor and Delivery to Postpartum Care. Tool: Information for Pregnant Patients About COVID-19 in 7 Different Languages (Pregistry)

Literature Review (Obstetrics): Gallery View, Grid View

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